Late port-site metastasis of unexpected gallbladder carcinoma after laparoscopic cholecystectomy: A case report.

INTRODUCTION: Incidental gallbladder carcinoma refers to a discovery of gallbladder cancer during or after cholecystectomy. Late port-site metastasis (PSM) following Laparoscopic cholecystectomy (LC) is rare with an incidence rate of 10.3%. PATIENT CONCERNS: We report a case of a 58-year-old man who presented with a painful abdominal wall mass for 6 weeks. He had a history of LC for symptomatic cholelithiasis, 8 years prior. DIAGNOSIS: Histopathological examination revealed a positive result for metastatic adenocarcinoma from the abdominal wall mass. Moreover, Positron emission tomography (PET) showed a small focus of intense fluorodeoxyglucose (FDG) uptake in the gallbladder bed, which was highly suspicious for malignancy. INTERVENTION: Decision was to proceed with surgery owing to uptake in the gallbladder bed with single-site metastasis to the previous port site. In addition, in the board meeting, an agreement was reached for performing distal pancreatectomy with splenectomy owing to uncertainty of malignancy based on what was discovered during the full metastatic workup. Diagnostic laparoscopy followed by midline laparotomy performed. Radical completion cholecystectomy with lymphadenectomy was done. Followed by complete resection of the anterior abdominal wall. Distal pancreatectomy and splenectomy were then performed. OUTCOME: Pathological diagnosis showed metastatic/invasive, moderately differentiated adenocarcinoma with positive margins on the posterior surface of excised port-site mass. The positive margins necessitated further chemoradiotherapy, followed by adjuvant chemotherapy until lung metastasis was identified. After this, the patient was scheduled for palliative chemotherapy. CONCLUSION: Presence of PSM is often associated with peritoneal metastasis. For this reason, it is advised to evaluate the patient for possible metastasis.

Awareness and Approaches Regarding Artificial Intelligence in Dentistry: A Scoping Review.

BACKGROUND: Dentistry is one of the unique specialties that deals with both humans and machines. This fact illustrates the strong potential for artificial intelligence (AI) implementation in dentistry, which makes awareness and attitude toward AI an important indicator for the future of this technology in the field. Hence, this scoping review aimed to report the status of awareness and attitude toward AI in dentistry. METHODOLOGY: To ensure the quality and transparency of the present review, the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) flow chart is reported. Four databases were searched for related topics (Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica database (EMBASE), Google Scholar, and Scopus); 1,430 studies were identified, and after screening and filtering, 21 cross-sectional studies were included. RESULTS: Twenty-one cross-sectional studies were included and yielded 7,688 participants. With an average level of 50.31% among all the studies that reported awareness (18 studies). Four subgroups' average levels of awareness toward AI in dentistry were reported: 67.16% among dentists, 42.58% among dental students, 45.56% for studies conducted on both dentists and dental students, and 69.53% for studies reporting awareness of AI in oral radiology. Regarding attitude, out of 13 studies, an average level of 44.13% felt threatened or thought AI would replace them. CONCLUSION: The average level of awareness is in accordance with the attitude toward AI in dentistry. The low levels of awareness are important indicators of the gap formed between the inevitable application of AI and the lack of utilization in the dental field. AI implementation in dental schools' curricula is required since the lowest reported level among subgroups was among dental students.

Vagus nerve stimulation in medically refractory epilepsy: Adverse effects and clinical correlates.

OBJECTIVES: To assess the frequency of adverse effects among pediatric and adult patients and the clinical variables associated with a higher probability of developing side effects. METHODS: This retrospective study enrolled pediatric and adult patients who underwent Vagus nerve stimulation (VNS) implantation at our institution and had documented follow-up during clinic visits for at least 6 months after implantation. Data collected included demographic information, epilepsy diagnosis, and device data. RESULTS: A total of 43 patients with drug-resistant epilepsy who received a VNS device at our institution were enrolled. The median follow-up period was 12 months. Fourteen patients (32.55%) reported no side effects from VNS therapy. Side effects ranged from mild to severe, with significant side effects observed in 8 patients. Data on therapy efficacy were collected, and 10 patients (23.26%) reported no change in seizure frequency following device implantation. CONCLUSION: This study demonstrates that VNS is an important adjunct treatment option for epilepsy patients. Dysphagia and dyspnea can be significant adverse effects leading to treatment discontinuation, aspiration pneumonia, intensive care unit (ICU) admission, and prolonged hospital stay. These effects are more frequent in patients with symptomatic generalized epilepsy, global developmental delay at baseline, previous ICU admissions, abnormal brain magnetic resonance imaging findings, and seizures with multiple semiologies.

Clinical outcomes of lower gastrointestinal bleeding in patients managed with lower endoscopy: A tertiary center results.

BACKGROUND: Lower gastrointestinal bleeding (LGIB) is an urgent presentation with increasing prevalence and remains a common cause of hospitalization. The clinical outcome can vary based on several factors, including the cause of bleeding, its severity, and the effectiveness of management strategies. The aim of this study is to provide a comprehensive report on the clinical outcomes observed in patients with LGIB who underwent lower endoscopy. METHODS: All patients who underwent emergency lower endoscopy for fresh bleeding per rectum, from May 2015 to December 2021, were included. The primary outcome was to identify the rate of rebleeding after initial control of bleeding. The second was to measure the clinical outcomes and the potential predictors leading to intervention and readmission. RESULTS: A total of 84 patients were included. Active bleeding was found in 20% at the time of endoscopy. Rebleeding within 90 days occurred in 6% of the total patients; two of which (2.38%) were within the same admission. Ninety-day readmission was reported in 19% of the cases. Upper endoscopy was performed in 32.5% of the total cases and was found to be a significant predictor for intervention (OR 4.1, P = 0.013). Personal history of inflammatory bowel disease (IBD) and initial use of sigmoidoscopy were found to be significant predictors of readmission [(OR 5.09, P = 0.008) and (OR 5.08, P = 0.019)]. CONCLUSIONS: LGIB is an emergency that must be identified and managed using an agreed protocol between all associated services to determine who needs upper GI endoscopy, ICU admission, or emergency endoscopy within 12 hours.

Life cycle assessment and cost-benefit analysis of nature-based solutions for contaminated land remediation: A mini-review.

Nature-based solutions (NbS) have gained significant attention as a promising approach for remediating contaminated lands, offering multiple ecosystem services (ESs) benefits beyond pollution mitigation. However, the quantitative sustainability assessment of NbS remediation systems, particularly with regard to post-remediation impacts, remains limited. This mini-review aims to address the existing gaps in the assessment of NbS remediation systems by evaluating the limitations of life cycle assessment (LCA) and cost-benefit analysis (CBA) methodologies. A systematic literature search was conducted resulting in the review of 44 relevant studies published between 2006 and 2023. The review highlights an increasing trend in the coverage in the sustainability assessment literature of NbS remediation systems. Phytoextraction was identified as the main NbS mechanism employed in 65 % of the reviewed works, targeting contaminants such as heavy metals and hydrocarbons. However, the post-remediation aspects, including impacts on ESs and the end-of-life management of NbS biomass, were often neglected in the assessments with only a subset of studies partially exploring such aspects. The findings underscore the need for a comprehensive and integrated approach to assess the sustainability of NbS remediation systems, including the incorporation of economic factors, site-specific considerations, and post-remediation impacts. Addressing these gaps will enhance the understanding of NbS effectiveness and facilitate informed decision-making for contaminated land remediation.

Does Social Media Affect a Patient's Decision to Undergo Orthognathic Surgery?

Orthognathic surgery, also known as corrective jaw surgery, is a procedure that corrects abnormalities of the jaw and face. It is used to treat malocclusions, where the teeth and jaws are misaligned. This surgery can improve the function and appearance of the jaw and face, leading to improved mastication, speech, and quality of life for the patients. To assess if social media had any effect on the patients' decision to undergo orthognathic surgery, a self-administered online questionnaire was distributed to patients who had undergone orthognathic surgery at the Oral and Maxillofacial department through the health information system (BESTCare, 2.0A) to participate in the study. In total, 111 responses were recorded from the patients, with 107 agreeing to answer the questionnaire and 4 refusing to answer. Twitter was a source of information about orthognathic surgery for 61 patients (57%). When using a social media platform, 3 patients (2.8%) were influenced by an advertisement or an educational post on social media that presented the surgical correction of the jaws, while 15 (14%) believed that they had been somewhat influenced, and 25 (23.4%) picked their surgeon through social media. Fifty-six patients (52.3%) took the neutral position regarding whether information on social media had answered their questions and concerns regarding the surgical procedure. Social media did not influence patients' decision to undergo the procedure. Surgeons and specialists must utilize their platforms to answer any concerns or questions from any patient undergoing or having undergone this corrective jaw surgery.

External Carotid Artery-Jugular Vein Fistula Caused by Blunt Trauma: A Case Report & Literature Review.

Acquired carotid-jugular fistula usually occurs due to neck stab wounds, gunshots, or central vein catheterization. Blunt trauma is a rare cause. These cases usually present with pulsatile swelling, tinnitus, and continued thrills in the neck. Both surgical and endovascular options have been used to manage these fistulas. Coil embolization is also applied in high-flow fistulas. We present a case of a 38-year-old woman free of any pre-existing medical conditions, presenting with a fistula between the external carotid artery and external jugular vein distally and with a high flow. She was treated with fistula embolization using coils while limiting the high flow via a balloon in the jugular vein. Our case highlights the possibility of using coils in high-flow fistulas in anatomically challenging fistulas. Furthermore, relevant literature review is presented to recapitulate unique features and effective management of carotid-jugular fistulas.

Prevalence and Predictors of Scoliosis and Back Pain in 591 Adolescents: A Randomized, Stratified, Cross-Sectional Study in Riyadh, Saudi Arabia.

Purpose Owing to the difficulty of establishing a screening program for scoliosis and back pain, along with their disabling consequences and the lack of local prevalence rates, we sought to study the prevalence of scoliosis and back pain in adolescents in Saudi Arabia and the burden reported by the affected age group on the health system. Materials and methods A school-based, cross-sectional pilot study covering all school districts in Riyadh, Saudi Arabia, was conducted. Students between 12 and 18 years of age were included. Students with any spinal or neurological disorders were excluded. Physical examinations to screen for scoliosis and student-filled questionnaires to assess back pain and health-related quality of life were performed. Results Of the 700 students, 591 met the inclusion criteria. High suspicion of adolescent idiopathic scoliosis (AIS) was considered in 174 students (29.44%). In addition, 45.42% of the students had a history of back pain. The Oswestry Disability Index showed that 87 students had disabilities. The average Scoliosis Research Society-22 score was 3 out of 5. A significant difference was found in the self-image and mental health domains for AIS (p = 0.04, p = 0.02, respectively). Age showed a significant increase in the odds ratio of a positive physical exam for every increase of one year in age (p < 0.01). Conclusion Identifying the prevalence rates and early associated factors during adolescence would help lower the burden on the health system and benefit public health in general. A nationwide study is required to identify the relationship between scoliosis and back pain.

Coin retained in the upper esophagus for more than 4 years: A case report and literature review.

Coins are among the most common foreign bodies ingested by children, especially those below 5 years of age. Early endoscopic retrieval of esophageal coins minimizes the risk of serious complications. However, significant morbidity and mortality are reported when coins are retained in the gastrointestinal tract for prolonged periods of time. We report a case in which a coin was retained in the upper esophagus for 4 years and presented a distinctive clinical course. An esophageal coin retained for a prolonged period may place the patient at a risk of complications such as tracheoesophageal fistulas. The management of patients with complicated aerodigestive tract foreign bodies is challenging. To avoid a delayed diagnosis and to improve the patients' safety, the quality of medical care in rural areas should be monitored by implementing continuous educational programs for primary physicians.

The Impacts on Greenhouse Gases Emission during the COVID-19 lockdown in the US: An Economic Input-Output Life Cycle Assessment.

The SARS-CoV-2 virus pandemic (COVID-19) is causing disruptions to energy, finance, tourism, and trade industries all around the world. These disruptions are the result of quarantining and lockdowns that cause reductions in production and consumptions. This change in production and consumption rates has environmental consequences. This study investigates the environmental effects of COVID-19 lockdown in the United States by Input-Output Life Cycle Assessment (IO-LCA) approach. The analysis is based on extraction of economic data in the US. The simulated results are based on different durations and strategies of lockdown measures. Among all industrial categories, utilities, which include power generation and supply, water supply, and natural gas supply sectors, saw the most significant reductions by approximately 110 kt CO2-eq in the first quarter and 265 kt CO2-eq in the second quarter of 2020. The assessed reductions were the results of both direct emission reductions caused by the shutdown of certain industries and also indirect emission reductions from upstream industries. The proposed methodology provides an effective guideline to predict the greenhouse gases emissions, which can be used as a prediction method for different regions in the world.

Non-ossifying Fibroma Pathological Fracture in a Patient With Lactose Intolerance.

Non-ossifying fibroma (NOF) is a frequently occurring benign tumor of children and adolescents. In the long bones, it appears as an eccentric, expanded lesion in the metaphyseal diaphyseal area. Most cases are asymptomatic and resolve at a later age while others might become symptomatic and have a high risk of fracture. We present a case of a 15-year-old boy who is known to have lactose intolerance, suffered a pathological fracture following trauma, and was diagnosed with non-ossifying fibroma of the proximal tibia. The etiology of these lesions is not well-known. However, there might be a relation between tendons and NOF. This reported case of NOF is in the proximal tibia, which is a common site of the lesion beside the distal femur. Our reported case was treated by open curettage and grafting, which is the recommended classical treatment. On follow-up, full union was achieved without complications.

Effect of shisha (waterpipe) smoking on lung functions and fractional exhaled nitric oxide (FeNO) among Saudi young adult shisha smokers.

Shisha (waterpipe) smoking is becoming a more prevalent form of tobacco consumption, and is growing worldwide, particularly among the young generation in the Middle East. This cross-sectional study aimed to determine the effects of shisha smoking on lung functions and Fractional Exhaled Nitric Oxide (FeNO) among Saudi young adults. We recruited 146 apparently healthy male subjects (73 control and 73 shisha smokers). The exposed group consisted of male shisha smokers, with mean age 21.54 ± 0.41 (mean ± SEM) range 17-33 years. The control group consisted of similar number (73) of non-smokers with mean age 21.36 ± 0.19 (mean ± SEM) range 18-28 years. Between the groups we considered the factors like age, height, weight, gender, ethnicity and socioeconomic status to estimate the impact of shisha smoking on lung function and fractional exhaled nitric oxide. Lung function test was performed by using an Spirovit-SP-1 Electronic Spirometer. Fractional Exhaled Nitric Oxide (FeNO) was measured by using Niox Mino. A significant decrease in lung function parameters FEV1, FEV1/FVC Ratio, FEF-25%, FEF-50%, FEF-75% and FEF-75-85% was found among shisha smokers relative to their control group. There was also a significant reduction in the Fractional Exhaled Nitric Oxide among Shisha smokers compared to control group.